WebNov 26, 2012 · INTRODUCTION. The CCCTC-binding factor, CTCF, is a ubiquitously expressed transcriptional regulator protein that is highly conserved from fly to man (1, 2).It was first identified as a transcriptional repressor of the MYC oncogene (3, 4) and, subsequently, has been shown to be involved in an extraordinarily diverse set of … WebCTCF (CFAP108, FAP108) protein expression summary. Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to …
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WebJun 28, 2024 · Ctcf haploinsufficient mice exhibit aberrant hypermethylation and increased spontaneous tumor formation within various organs . Using a similar model, we recently examined the effect of Ctcf haploinsufficiency on differential AS in several mouse tissues including brain, kidney, liver, muscle and spleen . Our analysis showed an overall ... WebCTCF = Integrated Density – (Area of selected cell X Mean fluorescence of background readings) Make a graph and your done. Notice that rounded up mitotic cells appear to have a much higher level ... guangzhou lighting fair 2014
Brain tissue expression of CTCF in Pituitary gland - The …
WebJan 28, 2024 · The DNA-binding protein CCCTC-binding factor (CTCF) and the cohesin complex function together to shape chromatin architecture in mammalian cells, but the molecular details of this process remain unclear. Here, we demonstrate that a 79-aa region within the CTCF N terminus is essential for cohesin positioning at CTCF binding sites … WebMar 11, 2014 · CCCTC-binding factor (CTCF) is a DNA-binding protein that has various, often seemingly contradictory, roles in gene regulation. This Review describes these … WebExpression of CTCF (CFAP108, FAP108) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. guangzhou lightfair 2022